Bilayers of nucleosome core particles.

  title={Bilayers of nucleosome core particles.},
  author={Am{\'e}lie Leforestier and Jacques Dubochet and Françoise Livolant},
  journal={Biophysical journal},
  volume={81 4},
Among the multiple effects involved in chromatin condensation and decondensation processes, interactions between nucleosome core particles are suspected to play a crucial role. We analyze them in the absence of linker DNA and added proteins, after the self-assembly of isolated nucleosome core particles under controlled ionic conditions. We describe an original lamellar mesophase forming tubules on the mesoscopic scale. High resolution imaging of cryosections of vitrified samples reveals how… CONTINUE READING