Bilateral spastic cerebral palsy--MRI pathology and origin. Analysis from a representative series of 56 cases.

Abstract

MRI of the brain was performed on 56 children with bilateral spastic cerebral palsy (CP) at a mean age of 10.7 years. Specific pathology was found in 91 per cent; periventricular leukomalacia was present in 42 per cent of term- and 87 per cent of preterm-born children. Parasagittal subcorticocortical injury, multicystic encephalomalacia and basal ganglia lesions were identified in 16 per cent, in all but one associated with severe peri-/neonatal events at term or near term. Maldevelopment comprised 9 per cent, all but one found in term-born children. MRI morphology correlated strikingly with outcome. Periventricular leukomalacia was associated with more severe disability in term- than preterm-born children.

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@article{KrgelohMann1995BilateralSC, title={Bilateral spastic cerebral palsy--MRI pathology and origin. Analysis from a representative series of 56 cases.}, author={Ingeborg Kr{\"a}geloh-Mann and Denise Petersen and Gudrun Hagberg and Brigitte Vollmer and Bengt A Hagberg and Ralph Michaelis}, journal={Developmental medicine and child neurology}, year={1995}, volume={37 5}, pages={379-97} }