Bilateral renal denervation can prevent the development of stress-induced hypertension in the borderline hypertensive rat.

@article{Lawler1989BilateralRD,
  title={Bilateral renal denervation can prevent the development of stress-induced hypertension in the borderline hypertensive rat.},
  author={James E. Lawler and Brian J Sanders and Robert H Cox and Venita Mitchell and Philip G Baer},
  journal={Clinical and experimental hypertension. Part A, Theory and practice},
  year={1989},
  volume={11 8},
  pages={1549-63}
}
The borderline hypertensive rat (BHR) shows large blood pressure responses to either stress or a high salt diet. Since the renal nerves have been shown to play a role in several animal models of hypertension, the current study sought to determine the effect of bilateral renal denervation on the development of stress-induced hypertension in the BHR. BHR were deprived of renal nerves under ether anesthesia after either 5 or 11 weeks of daily 2-hour stress sessions. Additional BHR received sham… CONTINUE READING