Bigger isn't better

Abstract

H IV-1 induces e x t e n s i v e changes in its host cell's nuclear pores, Monette et al. reveal. Like all viruses, HIV-1 hijacks the molecular machinery of its host cell to drive its own replication. One process disrupted by the virus is protein transport between the nucleus and cytoplasm. For example, HIV-1 prevents an RNA-binding protein called hnRNP A1… (More)

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