Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension.

@article{Rubens2001BigEA,
  title={Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension.},
  author={C. Rubens and R. Ewert and M. Halank and R. Wensel and H. Orzechowski and H. Schultheiss and G. Hoeffken},
  journal={Chest},
  year={2001},
  volume={120 5},
  pages={
          1562-9
        }
}
  • C. Rubens, R. Ewert, +4 authors G. Hoeffken
  • Published 2001
  • Medicine
  • Chest
  • STUDY OBJECTIVES Primary pulmonary hypertension (PPH) is a rare disease of unknown etiology that is characterized by a poor prognosis. This study was undertaken to investigate possible correlations between endothelin (ET)-1 and big ET-1 plasma levels and the severity of PPH. PATIENTS Sixteen consecutive patients with PPH were included. INTERVENTIONS Hemodynamics of patients with PPH were measured by right-heart catheterization, and a 6-min walk test was performed. MEASUREMENTS Plasma… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 25 REFERENCES