Bifunctional electro-optical nanoprobe to real-time detect local biochemical processes in single cells.

@article{Zheng2011BifunctionalEN,
  title={Bifunctional electro-optical nanoprobe to real-time detect local biochemical processes in single cells.},
  author={Xin Ting Zheng and Weihua Hu and Houxiao Wang and Hongbin Yang and Wei Zhou and Chang Ming Li},
  journal={Biosensors & bioelectronics},
  year={2011},
  volume={26 11},
  pages={4484-90}
}
A bifunctional electro-optical nanoprobe with integrated nanoring electrode and optical nanotip was fabricated and investigated to simultaneously detect both electrical and optical signals in real-time with high spatial resolution. Concurrent measurements of the oxidant generation and the intracellular antioxidant levels in single cells correlate the stronger oxidant generation with an altered initial antioxidant response in the breast cancer cells in comparison to the normal ones suggesting… CONTINUE READING