Biflavonoids with cytotoxic and antibacterial activity from Ochna macrocalyx.

  title={Biflavonoids with cytotoxic and antibacterial activity from Ochna macrocalyx.},
  author={Sharon Lam Po Tang and Paul D. Bremner and Andreas Kortenkamp and Christina Schlage and Alexander Irvine Gray and Simon Gibbons and Michael Heinrich},
  journal={Planta medica},
  volume={69 3},
Six biflavonoid and related compounds were isolated from the ethanolic extract of Ochna macrocalyx bark. One is a new compound, the isoflavanone dimer dehydroxyhexaspermone C ( 1). Previously isolated compounds obtained from the bark are biisoflavonoid hexaspermone C ( 2). tetrahydrofuran derivative ochnone ( 3). furobenzopyran derivative cordigol ( 4). and biflavonoids calodenin B ( 5). and dihydrocalodenin B ( 6). Although 3 has already been isolated, its spectral data are presented here for… 
Antibacterial and cytotoxic biflavonoids from the root bark of Ochna kirkii.
Isolation of biflavonoids and related secondary metabolites from O. kirkii demonstrates their chemotaxonomic significance to the genus Ochna and to other members of the family Ochnaceae.
A novel antimicrobial flavonoid from the stem bark of Commiphora pedunculata (Kotschy & Peyr.) Engl.
A new flavonoid, 2-(3,5-dihydroxy-4-methoxy-phenyl)-3,5-dihydroxy-8,8-dimethyl-2,3-dihydro-8H-pyrano[3,2]chromen-4-one, together with previously reported epicatechin was isolated from the ethyl
Bioactive (+)-Catechin-3ꞌ-O-rhamnopyranoside from Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae)
ABSTRACT In this study, a flavan-3-ol glycoside, (+)-catechin-3ꞌ-O-rhamnopyranoside isolated from the stem bark extract of N. macrophylla was evaluated for its antivenom, analgesic,
Biflavonoids from an Ethno-Medicinal Plant Ochna holtzii Gilg
The extracts and the isolated constituents showed varying levels of activities against the microbes, and none of these matched those of the antibiotic Chloramphenicol or the antifungal Fluconazole.
Antimicrobial activity of stigmasterol from the stem bark of Neocarya macrophylla
Background:  Natural products play a significant role in human therapy. They represent a huge reservoir of bioactive chemical diversity and help in understanding the cellular pathways that are
Preliminary phytochemical and antimicrobial investigations of leaf extracts of Ochna schweinfurthiana (Ochnaceae).
The antimicrobial activity of the acetone and methanol extracts of the leaves of Ochna schweinfurthiana F Hoffm obtained through maceration was evaluated and validates the ethno-medical use in wound dressing and other forms of bacterial infections.
(3,3″)-Linked Biflavanones from Ouratea spectabilis and Their Effects on the Release of Proinflammatory Cytokines in THP-1 Cells.
Findings show ouratein D as a selective CCL2 inhibitor, which may have potential for the development of new anti-inflammatory agents to prevent or treat cardiovascular diseases.
Flavonoids with antimicrobial activity from the stem bark of Commiphora pedunculata (Kotschy & Peyr.) Engl.
The first reported investigation into the phytochemical constituents of Commiphora pedunculata led to the isolation of two flavonoids: kaempferol and dihydrokaempferol from the ethyl acetate-soluble
Antibacterial, antiviral, antiproliferative and apoptosis‐inducing properties of Brackenridgea zanguebarica (Ochnaceae)
The bark extract of B. zanguebarica had a pronounced activity against free HSV‐1 and a strong antibacterial activity against Gram‐positive strains, which are often involved in skin infections.
Chemical composition, antioxidant and antibacterial activities and evaluation of cytotoxicity of the fractions obtained from Selaginella convoluta (Arn.) Spring (Selaginellaceae)
ABSTRACT The aim of this study was to evaluate the chemical composition, antioxidant and antibacterial activities and cytotoxicity of fractions from Selaginella convoluta, obtained by liquid–liquid