Bifidobacterium breve enhances transforming growth factor beta1 signaling by regulating Smad7 expression in preterm infants.

@article{Fujii2006BifidobacteriumBE,
  title={Bifidobacterium breve enhances transforming growth factor beta1 signaling by regulating Smad7 expression in preterm infants.},
  author={Tohru Fujii and Yoshikazu Ohtsuka and Tsubasa Lee and Takahiro Kudo and Hiromichi Shoji and Hiroaki Sato and Satoru Nagata and Toshiaki Shimizu and Yuichiro Yamashiro},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={2006},
  volume={43 1},
  pages={83-8}
}
OBJECTIVES Transforming growth factor (TGF) beta1 displays a broad spectrum of activities in mucosal regulation, including induction of oral tolerance, potent anti-inflammatory effects, mucosal IgA expression and effects on epithelial cell proliferation and differentiation. The present study examined the effect of probiotics on the immunologic system of preterm infants in relation to TGF-beta signaling. METHODS Subjects comprised 19 preterm infants divided into 2 groups: receiving… CONTINUE READING

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