Bidirectionalization of polar promoters in plants

  title={Bidirectionalization of polar promoters in plants},
  author={Mingtang Xie and Yuehui He and Susheng Gan},
  journal={Nature Biotechnology},
A typical eukaryotic promoter consists of a minimal promoter and other upstream cis elements. The minimal promoter is essentially a TATA box region where RNA polymerase II, TATA-binding protein (TBP), and TBP-associated factors (TAFs) bind to initiate transcription, but minimal promoters alone have no transcriptional activity. The cis elements, to which tissue-specific or development-specific transcription factors bind, individually or in combination, determine the spatio-temporal expression… CONTINUE READING