Bidirectional regulation of angiogenesis by phytoestrogens through estrogen receptor-mediated signaling networks.

Abstract

Sex hormone estrogen is one of the most active intrinsic angiogenesis regulators; its therapeutic use has been limited due to its carcinogenic potential. Plant-derived phytoestrogens are attractive alternatives, but reports on their angiogenic activities often lack in-depth analysis and sometimes are controversial. Herein, we report a data-mining study with… (More)
DOI: 10.1016/S1875-5364(16)30024-3

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