Bidirectional communication between oocytes and follicle cells: ensuring oocyte developmental competence.

  title={Bidirectional communication between oocytes and follicle cells: ensuring oocyte developmental competence.},
  author={Gerald M. Kidder and Barbara C Vanderhyden},
  journal={Canadian journal of physiology and pharmacology},
  volume={88 4},
Female fertility is determined to a large extent by the quality (developmental competence) of the oocyte as reflected in its ability to undergo meiosis, be fertilized, and give rise to a healthy embryo. Growth of the mammalian oocyte is coordinated with that of the follicle that encloses it by the actions of signals that pass in both directions between the germline and somatic components. This review summarizes what is known about the roles played by 2 different modes of intrafollicular… CONTINUE READING


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