Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles

Abstract

Electron microscope immunocytochemistry reveals that both anterograde-directed (proinsulin and VSV G protein) and retrograde-directed (the KDEL receptor) cargo are present in COPI-coated vesicles budding from every level of the Golgi stack in whole cells; however, they comprise two distinct populations that together can account for at least 80% of the… (More)
DOI: 10.1016/S0092-8674(00)80341-4

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@article{Orci1997BidirectionalTB, title={Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles}, author={Lelio Orci and Mark Stamnes and Mariella Ravazzola and Myl{\`e}ne Amherdt and Alain Perrelet and Thomas H. S{\"{o}llner and James E Rothman}, journal={Cell}, year={1997}, volume={90}, pages={335-349} }