Bidirectional Transfer Study of Polystyrene Nanoparticles across the Placental Barrier in an ex Vivo Human Placental Perfusion Model.

@article{Grafmueller2015BidirectionalTS,
  title={Bidirectional Transfer Study of Polystyrene Nanoparticles across the Placental Barrier in an ex Vivo Human Placental Perfusion Model.},
  author={Stefanie Grafmueller and Pius Manser and Liliane Diener and P O Diener and Xenia Maeder-Althaus and Lionel Maurizi and Wolfram Jochum and Harald F Krug and Tina Buerki-Thurnherr and Ursula von Mandach and Peter Wick},
  journal={Environmental health perspectives},
  year={2015},
  volume={123 12},
  pages={1280-6}
}
BACKGROUND Nanoparticle exposure in utero might not be a major concern yet, but it could become more important with the increasing application of nanomaterials in consumer and medical products. Several epidemiologic and in vitro studies have shown that nanoparticles can have potential toxic effects. However, nanoparticles also offer the opportunity to develop new therapeutic strategies to treat specifically either the pregnant mother or the fetus. Previous studies mainly addressed whether… CONTINUE READING