Bidirectional Role of Tumor Necrosis Factor-in Coronary Microembolization Progressive Contractile Dysfunction Versus Delayed Protection Against Infarction

@inproceedings{Skyschally2006BidirectionalRO,
  title={Bidirectional Role of Tumor Necrosis Factor-in Coronary Microembolization Progressive Contractile Dysfunction Versus Delayed Protection Against Infarction},
  author={Andreas Skyschally and Petra Gres and Simone Hoffmann and Michael Haude and R. Erbel and Rainer Schulz and Gerd Heusch},
  year={2006}
}
In patients with unstable angina, plaque rupture and coronary microembolization (ME) can precede complete coronary artery occlusion and impending infarction. ME-induced microinfarcts initiate an inflammatory reaction with increased tumor necrosis factor(TNF) expression, resulting in progressive contractile dysfunction. However, TNFis not only a negative… CONTINUE READING