Bidder's organ in the toad Bufo marinus: Effects of orchidectomy on the morphology and expression of lamina‐associated polypeptide 2

@article{Brown2002BiddersOI,
  title={Bidder's organ in the toad Bufo marinus: Effects of orchidectomy on the morphology and expression of lamina‐associated polypeptide 2},
  author={Federico D. Brown and Eugenia M Del Pino and Georg Krohne},
  journal={Development},
  year={2002},
  volume={44}
}
The Bidder's organ is an undeveloped ovary located anterior to the testis in male true toads (Bufonidae). The presence of sperm and oocytes, derived from the primordial germ cells of the male toad, provides an exceptional condition for the study of germ cell differentiation in vertebrates. In this study, the effects of orchidectomy on morphology and on lamina‐associated polypeptide 2 (LAP2) expression were investigated in the Bidder's organ of Bufo marinus. To characterize bidderian oocytes… 
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27 Citations

The Bidder's organ of the toad Rhinella arenarum (Amphibia, Anura). Presence of steroidogenic enzymes.
TLDR
It is found that BOs weight was significantly lower in males during the pre-reproductive period and that there is no significant correlation between the weights of BO and the adjacent testis, which confirm the steroidogenic capacity of the BO in adult males of R. arenarum.
Development and steroidogenic properties of the Bidder's organ of the tadpole of Rhinella arenarum (Amphibia, Anura).
TLDR
BO is able to synthesize estradiol from endogenous precursors and proper gonad remains undifferentiated at least until the end of the metamorphosis.
Molecular characterization of the Bidder's organ in the cane toad (Bufo marinus).
TLDR
It is demonstrated that Sf1, Dax1, and p450arom, key genes involved in vertebrate steroidogenesis, are transcriptionally active in the BO during developmental milestones associated with sexual development and maturation, suggesting that the BO likely has a steroidogenic role in the development of the cane toad, distinct from that of the gonads.
Estradiol production by the Bidder's organ of the toad Rhinella arenarum (Amphibia, Anura). Seasonal variations in plasma estradiol.
TLDR
Seasonal variations in plasma E(2), in bidderian total activity of aromatase and, that the BO of adult males of R. arenarum is able to produce E( 2) from endogenous substrates throughout the year are demonstrated.
Morphological and histochemical studies of Bidder’s organ in Rhinella schneideri (Amphibia: Anura) males
TLDR
Specific aspects related to the morphological description of the Bidder’s organ in males of the neotropical frog Rhinella schneideri during the breeding season are described with emphasis on architecture, morphometry and histochemistry.
Morphological Aspects of Gonadal Morphogenesis in Bufo bufo (Amphibia anura): Bidder's Organ Differentiation
TLDR
The asymmetric model, in which there is a tendency toward a primary female differentiation, was confirmed, and the female differentiation becomes stable in the Bidder's organ because of the absence of further interaction between germ and medullary somatic cells, which would have led toward a male differentiation.
LPS-induced alterations in reproductive organs and liver pigmentation in the toad Rhinella diptycha (Bufonidae)
TLDR
The results suggest that LPS delays the release of spermatozoa, possibly due to alterations in serum levels of testosterone and (or) gonadotropins, which may also explain fewer degrading cells in Bidder’s organ.
Flutamide effects on morphology of reproductive organs and liver of Neotropical Anura, Rhinella schneideri.
Ultrastructural aspects of gonadal morphogenesis in Bufo bufo (Amphibia Anura) 1. Sex differentiation.
TLDR
The morphogenesis of gonads in Bufo bufo tadpoles was studied, and ultrastructural differences between sexes were identified, finding that sex differentiation follows an "asymmetric" pattern in which germ cells tend primarily toward a female differentiation and male differentiation depends on a secondary interaction between germ cells and medullary somatic cells.
Bidder's organ--structure, development and function.
TLDR
The development and structure of Bidder's organs are described, the knowledge on gene expression and steroidogenic activity in these organs are summarized, and hypotheses regarding Bidder’s organ function are presented.
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