Bid regulates the immunological profile of murine microglia and macrophages.

@article{Mayo2011BidRT,
  title={Bid regulates the immunological profile of murine microglia and macrophages.},
  author={Lior Mayo and Ayelet Levy and Jasmine Jacob-Hirsch and Ninette Amariglio and Gideon Rechavi and Reuven Stein},
  journal={Glia},
  year={2011},
  volume={59 3},
  pages={397-412}
}
Apoptosis is a controlled cell-death process mediated inter alia by proteins of the Bcl-2 family. Some proteins previously shown to promote the apoptotic process were found to have nonapoptotic functions as well. Microglia, the resident immune cells of the central nervous system, respond to brain derangements by becoming activated to contend with the brain damage. Activated microglia can also undergo activation-induced cell death. Previous studies have addressed the role of core apoptotic… CONTINUE READING

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