Bicarbonate-stimulated [14C]butyrate uptake in basolateral membrane vesicles of rat distal colon.

BACKGROUND The mechanism of short-chain fatty acid (SCFA) absorption by the colon is not known. The aim of these experiments was to identify the transport mechanisms present in the basolateral membrane to develop an overall model of colonic SCFA absorption. METHODS These studies determined the uptake of [14C]butyrate (used as a model SCFA) by basolateral… CONTINUE READING