Bicarbonate Transport Along the Loop of Henle

  title={Bicarbonate Transport Along the Loop of Henle},
  author={Giovambattista Capasso and Robert Unwin and Samuel K. Agulian and Gerhard Giebisch},
Wemicroperfused the loop of Henle (LOH) to assess its contribution to urine acidification in vivo. Under control conditions (Na HCO3= 13 mM,perfusion rate 17 nl/min-') net bicarbonate transport (JHCO-) was unsaturated, flowand concentration-dependent, and increased linearly until a bicarbonate load of 1,400 pmols minwas reached. Methazolamide (2-10-4 M… CONTINUE READING