Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH.

@article{Olsnes1987BicarbonatechlorideAI,
  title={Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH.},
  author={Sjur Olsnes and Jannikke Ludt and Tor Inge T\onnessen and Kirsten Sandvig},
  journal={Journal of cellular physiology},
  year={1987},
  volume={132 2},
  pages={192-202}
}
The rates of bicarbonate-dependent uptake and efflux of 22Na+ in Vero cells were studied and compared with the uptake and efflux of 36Cl-. Both processes were strongly inhibited by DIDS. Whereas the transport of chloride increased approximately ten-fold when the internal pH was increased over a narrow range around neutrality, the uptake of Na+ was much less affected by changes in pH. The bicarbonate-linked uptake of 22Na+ was dependent on internal Cl- but not on internal Na+. At a constant… CONTINUE READING

From This Paper

Topics from this paper.
3 Citations
0 References
Similar Papers