Biaxial deformation of collagen and elastin fibers in coronary adventitia.

  title={Biaxial deformation of collagen and elastin fibers in coronary adventitia.},
  author={Huan Chen and Mikhail N Slipchenko and Yi Liu and Xuefeng Zhao and Ji-xin Cheng and Yoram Lanir and Ghassan S. Kassab},
  journal={Journal of applied physiology},
  volume={115 11},
The microstructural deformation-mechanical loading relation of the blood vessel wall is essential for understanding the overall mechanical behavior of vascular tissue in health and disease. We employed simultaneous mechanical loading-imaging to quantify in situ deformation of individual collagen and elastin fibers on unstained fresh porcine coronary adventitia under a combination of vessel inflation and axial extension loading. Specifically, the specimens were imaged under biaxial loads to… CONTINUE READING
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