Biased random walk model for the prioritization of drug resistance associated proteins

Abstract

Multi-drug resistance is the main cause of treatment failure in cancer patients. How to identify molecules underlying drug resistance from multi-omics data remains a great challenge. Here, we introduce a data biased strategy, ProteinRank, to prioritize drug-resistance associated proteins in cancer cells. First, we identified differentially expressed… (More)
DOI: 10.1038/srep10857

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