Biased expression of T cell receptor V beta genes in periodontitis patients.

@article{Yamazaki1996BiasedEO,
  title={Biased expression of T cell receptor V beta genes in periodontitis patients.},
  author={Kazushisa Yamazaki and Takako Eguchi Nakajima and Erica Gemmell and Margrethe Kjeldsen and Gregory John Seymour and Kohji Hara},
  journal={Clinical and experimental immunology},
  year={1996},
  volume={106 2},
  pages={329-35}
}
The aim of the present study was to investigate the hypothesis that there is selective activation and expansion of a limited repertoire of T cell receptor (TCR)-bearing T cells in periodontitis tissue. We studied TCR V beta gene expression in gingival tissues of periodontitis lesions and compared these with peripheral blood mononuclear cells (PBMC) from the same patients using polymerase chain reaction (PCR) amplification with 22 V beta-specific sense primers in combination with a common… CONTINUE READING