Biased T-cell receptor delta element recombination in scid thymocytes.

Abstract

Thymocytes in mutant mice with severe combined immunodeficiency (scid thymocytes) show ongoing recombination of some T-cell receptor delta gene elements, generating signal joints quantitatively and qualitatively indistinguishable from those in wild-type fetal thymocytes. Excised D delta 2-J delta 1 and D delta 1-D delta 2 rearrangements are detectable at… (More)

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Cite this paper

@article{Carroll1993BiasedTR, title={Biased T-cell receptor delta element recombination in scid thymocytes.}, author={Alan M. Carroll and Jill K. Slack and Wen Tzu Chang}, journal={Molecular and cellular biology}, year={1993}, volume={13 6}, pages={3632-40} }