Biased Brownian stepping rotation of FoF1-ATP synthase driven by proton motive force.

@article{Watanabe2013BiasedBS,
  title={Biased Brownian stepping rotation of FoF1-ATP synthase driven by proton motive force.},
  author={Ryoyu Watanabe and Kazuhito V. Tabata and Ryota Iino and Hiroshi Ueno and Masayuki Iwamoto and Shigetoshi Oiki and Hiroyuki Noji},
  journal={Nature communications},
  year={2013},
  volume={4},
  pages={
          1631
        }
}
FoF1-ATP synthase (FoF1) produces most of the ATP in cells, uniquely, by converting the proton motive force (pmf) into ATP production via mechanical rotation of the inner rotor complex. Technical difficulties have hampered direct investigation of pmf-driven rotation, which are crucial to elucidating the chemomechanical coupling mechanism of FoF1. Here we develop a novel supported membrane system for direct observation of the rotation of FoF1 driven by pmf that was formed by photolysis of caged… CONTINUE READING
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