Bias in the introduction of variation as an orienting factor in evolution

@article{Yampolsky2001BiasIT,
  title={Bias in the introduction of variation as an orienting factor in evolution},
  author={L. Yampolsky and A. Stoltzfus},
  journal={Evolution \& Development},
  year={2001},
  volume={3}
}
SUMMARY According to New Synthesis doctrine, the direction of evolution is determined by selection and not by “internal causes” that act by way of propensities of variation. This doctrine rests on the theoretical claim that because mutation rates are small in comparison to selection coefficients, mutation is powerless to overcome opposing selection. Using a simple population‐genetic model, this claim is shown to depend on assuming the prior availability of variation, so that mutation may act… Expand
Understanding bias in the introduction of variation as an evolutionary cause
TLDR
Modeling the influence of biases in the introduction process reveals behavior previously unimagined, as well as behavior previously considered impossible, in the course of evolution. Expand
Climbing mount probable: mutation as a cause of nonrandomness in evolution.
TLDR
A new analysis partitioning the variance in mean rates of amino acid replacement during human-chimpanzee divergence to components of codon mutation and amino acid exchangeability indicates that mutational effects are not merely important but account for most of the variance explained. Expand
The effect of development on the direction of evolution: toward a twenty‐first century consensus
  • W. Arthur
  • Biology, Medicine
  • Evolution & development
  • 2004
TLDR
It is suggested that developmental bias may provide a focal point for the coming together of conceptual and practical approaches to evo‐devo, and the extent to which bias is already incorporated in quantitative genetic studies. Expand
Why we don’t want another “Synthesis”
TLDR
Though evolutionary biology is not governed by any master theory, and incorporates views excluded from the OMS, the recognition of these changes has been hindered by woolly conceptions of theories, and by historical accounts common in the evolutionary literature that misrepresent the disputes that defined the OS. Expand
The interaction between developmental bias and natural selection: from centipede segments to a general hypothesis
TLDR
Here, the key concept of developmental bias is examined, which encompasses both developmental constraint and developmental drive, and how it is their interaction, rather than either process on its own, that determines evolutionary direction. Expand
The Role of Mutation Bias in Adaptive Evolution.
TLDR
Little support is found for mutation bias as an independent force in adaptive evolution, although it can interact with selection under conditions of small population size and when standing genetic variation is limited, entirely consistent with standard evolutionary theory. Expand
Mutationism and the dual causation of evolutionary change
TLDR
The synthetic challenge presented by these innovations is to integrate mutation‐and‐altered‐development into a new understanding of the dual causation of evolutionary change—a broader and more predictive understanding that already can lay claim to important empirical and theoretical results—and to develop a research program appropriately emphasizing the emergence of variation as a cause of propensities of evolutionarychange. Expand
Mutation-biased adaptation in Andean house wrens
TLDR
A case is proposed of mutation-biased adaptation, in which the course of evolution reflects both a bias in mutation and a fitness benefit, and how important are mutational biases in shaping adaptation is questioned. Expand
Constructive neutral evolution: exploring evolutionary theory’s curious disconnect
TLDR
Constructive neutral evolution provides a way to explore its most significant implications about the role of variation in evolution, and lays claim to important theoretical, experimental, and practical results. Expand
Mutation bias can shape adaptation in large asexual populations experiencing clonal interference
TLDR
This work considers the behavior of two simultaneously adapting traits, one with larger mutation rate U, the other with larger selection coefficient s, using asexual traveling wave models and finds that adaptation is dominated by whichever trait has the faster rate of adaptation v in isolation, with the other trait subject to evolutionary stalling. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 66 REFERENCES
On the Possibility of Constructive Neutral Evolution
  • A. Stoltzfus
  • Biology, Medicine
  • Journal of Molecular Evolution
  • 1999
TLDR
Nonselective factors in evolutionary innovation and directionality can be addressed in neutral models, such as those elaborated here with regard to scrambled ciliate genes, gRNA-mediated RNA editing, the transition from self-splicing to spliceosomal splicing, and the retention of duplicate genes. Expand
Developmental Constraints and Evolution: A Perspective from the Mountain Lake Conference on Development and Evolution
TLDR
This review distinguishes between "universal" and "local" constraints; it deals primarily with the latter, which apply to a limited range of taxa and can be broken even within the taxa to which they apply, though with varying degrees of difficulty. Expand
Directional mutation pressure and neutral molecular evolution.
  • N. Sueoka
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1988
TLDR
Analysis of DNA sequence has revealed that practically all organisms are subject to directional mutation pressure, and the theory offers plausible explanations for the large heterogeneity in guanine-plus-cytosine content among different parts of the vertebrate genome. Expand
The Genetical Theory of Natural Selection
PROBABLY most geneticists to-day are some-what sceptical as to the value of the mathematical treatment of their problems. With the deepest respect, and even awe, for that association of complexExpand
How the Leopard Changed Its Spots: The Evolution of Complexity
TLDR
Brian Goodwin argues clearly and persuasively that there is another explanation for the origin and diversity of species and admits that complexity is an inherent and emergent quality of life, and not merely the result of random mutation and natural selection. Expand
Individuals, hierarchies and processes: towards a more complete evolutionary theory
TLDR
It is urged that interlevel causation should feature centrally in explanatory hypotheses of evolution, and upward causation from genome dynamics to the directed introduction of mutants may be more important in a given case. Expand
Mutation rates differ among regions of the mammalian genome
TLDR
It is proposed that the differences arising because mutation patterns vary with the timing of replication of different chromosomal regions in the germline can account for both the origin of isochores in mammalian genomes and the observation that silent nucleotide substitutions in different mammalian genes do not have the same molecular clock. Expand
The meaning of evolution.
TLDR
In this essay it is attempted to show that the word evolution is currently used in at least three quite separate senses. Expand
Parallel molecular evolution of deletions and nonsense mutations in bacteriophage T7.
TLDR
The results suggest caution when reconstructing ancestral states of characters under directional selection, as well as caution against giving undue phylogenetic weight to insertion-deletion events. Expand
Nonrandom Patterns of Mutation are Reflected in Evolutionary Divergence and May Cause Some of the Unusual Patterns Observed in Sequences
TLDR
These processes will be the subject of this chapter and although only some fragments of information are beginning to become apparent, many of them are contrary to common expectations. Expand
...
1
2
3
4
5
...