Bias in estimating the causal hazard ratio when using two-stage instrumental variable methods.

@article{Wan2015BiasIE,
  title={Bias in estimating the causal hazard ratio when using two-stage instrumental variable methods.},
  author={Fei Wan and Dylan S. Small and Justin E. Bekelman and Nandita Mitra},
  journal={Statistics in medicine},
  year={2015},
  volume={34 14},
  pages={2235-65}
}
Two-stage instrumental variable methods are commonly used to estimate the causal effects of treatments on survival in the presence of measured and unmeasured confounding. Two-stage residual inclusion (2SRI) has been the method of choice over two-stage predictor substitution (2SPS) in clinical studies. We directly compare the bias in the causal hazard ratio… CONTINUE READING