Bi-directional interconversion of brite and white adipocytes

@article{Rosenwald2013BidirectionalIO,
  title={Bi-directional interconversion of brite and white adipocytes},
  author={Matthias Rosenwald and Aliki Perdikari and Thomas R{\"u}licke and Christian Wolfrum},
  journal={Nature Cell Biology},
  year={2013},
  volume={15},
  pages={659-667}
}
Brown adipose tissue helps to maintain body temperature in hibernators, rodents and neonatal mammals by converting lipids and glucose into heat, thereby increasing energy expenditure. In addition to classical brown adipocytes, adult rodents—like adult humans—harbour brown-like adipocytes in the predominantly white adipose tissue. The formation of these brite (brown-in-white) adipocytes is a physiological response to chronic cold and their cellular origin is under debate. We show here that cold… 
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The adipocyte browning process is a phenomenon that consists in the molecular and morphological remodeling of preadipocytes or mature white adipocytes into multilocular beige fat cells expressing…
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