Bi-directional interconversion of brite and white adipocytes

  title={Bi-directional interconversion of brite and white adipocytes},
  author={Matthias Rosenwald and Aliki Perdikari and Thomas R{\"u}licke and C. Wolfrum},
  journal={Nature Cell Biology},
  • Matthias Rosenwald, Aliki Perdikari, +1 author C. Wolfrum
  • Published 2013
  • Biology, Medicine
  • Nature Cell Biology
  • Brown adipose tissue helps to maintain body temperature in hibernators, rodents and neonatal mammals by converting lipids and glucose into heat, thereby increasing energy expenditure. In addition to classical brown adipocytes, adult rodents—like adult humans—harbour brown-like adipocytes in the predominantly white adipose tissue. The formation of these brite (brown-in-white) adipocytes is a physiological response to chronic cold and their cellular origin is under debate. We show here that cold… CONTINUE READING
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