Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure.

A complex interaction exists between elements of the host innate immune system and viral pathogens. It is essential that the host mount a robust immune response during viral infection and effectively resolve inflammation once the pathogen has been eliminated. Members of the nucleotide-binding domain leucine-rich repeat [NBD-LRR; known as NOD-like receptor… CONTINUE READING