Beyond the increasing complexity of the immunomodulatory HLA-G molecule.

@article{Carosella2008BeyondTI,
  title={Beyond the increasing complexity of the immunomodulatory HLA-G molecule.},
  author={Edgardo D. Carosella and Beno{\^i}t Favier and Nathalie Rouas-Freiss and Philippe Moreau and Joel Lemaoult},
  journal={Blood},
  year={2008},
  volume={111 10},
  pages={4862-70}
}
Human leukocyte antigen G (HLA-G) is a nonclassic major histocompatibility complex (MHC) class I molecule that functions as an immunomodulatory molecule capable of protecting fetal tissues from the maternal immune system. The relevance of HLA-G in other contexts was investigated soon afterward. Numerous studies have sought (and some have shown) the relevance of HLA-G in pathologic conditions, such as transplantation, autoimmunity, and cancer and hematologic malignancies. One of the main goals… CONTINUE READING

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