Beyond the Medial Regions of Prefrontal Cortex in the Regulation of Fear and Anxiety

@article{Shiba2016BeyondTM,
  title={Beyond the Medial Regions of Prefrontal Cortex in the Regulation of Fear and Anxiety},
  author={Yoshiro Shiba and Andrea M. Santangelo and Angela C. Roberts},
  journal={Frontiers in systems neuroscience},
  year={2016},
  volume={10},
  pages={12}
}
Fear and anxiety are adaptive responses but if left unregulated, or inappropriately regulated, they become biologically and socially maladaptive. Dysregulated emotions are manifest in a wide variety of psychiatric and neurological conditions but the external expression gives little indication of the underlying causes, which are inevitably multi-determined. To go beyond the overt phenotype and begin to understand the causal mechanisms leading to conditions characterized by anxiety and disorders… CONTINUE READING
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