Beyond the Dopamine Receptor the DARPP-32/Protein Phosphatase-1 Cascade

@article{Greengard1999BeyondTD,
  title={Beyond the Dopamine Receptor the DARPP-32/Protein Phosphatase-1 Cascade},
  author={Paul Greengard and P B Allen and Angus C. Nairn},
  journal={Neuron},
  year={1999},
  volume={23},
  pages={435-447}
}
striatum, and therefore function to integrate all input to Introduction this brain region. DARPP-32 is expressed in very high Of the many slow-acting neurotransmitters utilized by concentration (z50 mM) in virtually all medium spiny the mammalian central nervous system, dopamine has neurons (Ouimet et al., 1984, 1998) (Figure 2). Medium received by far the most attention. There are major medispiny neurons contain both D1 class (D1, D5) and D2 class cal reasons for this interest in understanding… CONTINUE READING
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