Beyond nucleic acid base pairs: from triads to heptads.

  title={Beyond nucleic acid base pairs: from triads to heptads.},
  author={J{\"u}rgen S{\"u}hnel},
  volume={61 1},
Hydrogen-bonded base pairs are an important determinant of nucleic acid structure and function. However, other interactions such as base-base stacking, base-backbone, and backbone-backbone interactions as well as effects exerted by the solvent and by metal or NH(4)(+) ions also have to be taken into account. In addition, hydrogen-bonded base complexes involving more than two bases can occur. With the rapidly increasing number and structural diversity of nucleic acid structures known at atomic… CONTINUE READING

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