Beyond lysis: how complement influences cell fate.

  title={Beyond lysis: how complement influences cell fate.},
  author={Duncan S. Cole and B. Paul Morgan},
  journal={Clinical science},
  volume={104 5},
Complement is a central component of the innate immune system involved in protection against pathogens. For many years, complement has been known to cause death of targets, either indirectly by attracting and activating phagocytes or directly by formation of a membrane pore, the membrane attack complex. More recently, it has been recognized that complement may cause other 'non-classical' effects that may not directly be aimed at killing of pathogens. Products of complement activation… CONTINUE READING
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