Beyond islands (extended abstract): runs in clone-probe matrices

  title={Beyond islands (extended abstract): runs in clone-probe matrices},
  author={David Bruce Wilson and David S. Greenberg and Cynthia A. Phillips},
Physical mapping is a fundamental component of the human genome project. A physical map consists of a set of probes which mark unique positions on a long fragment of DNA, together with the relative order of the probes on the DNA. This order is inferred from clone-probe hybridization experiments, which determine the probes contained within various fragments of the genome. In practice, the order of the probes is not completely determined by the hybridization experiments. To better design these… CONTINUE READING

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