Beyond conventional antibiotics for the future treatment of methicillin-resistant Staphylococcus aureus infections: two novel alternatives.

@article{FitzgeraldHughes2012BeyondCA,
  title={Beyond conventional antibiotics for the future treatment of methicillin-resistant Staphylococcus aureus infections: two novel alternatives.},
  author={Deirdre Fitzgerald-Hughes and Marc Devocelle and Hilary Humphreys},
  journal={FEMS immunology and medical microbiology},
  year={2012},
  volume={65 3},
  pages={399-412}
}
The majority of antibiotics currently used to treat methicillin-resistant Staphylococus aureus (MRSA) infections target bacterial cell wall synthesis or protein synthesis. Only daptomycin has a novel mode of action. Reliance on limited targets for MRSA chemotherapy, has contributed to antimicrobial resistance. Two alternative approaches to the treatment of S. aureus infection, particularly those caused by MRSA, that have alternative mechanisms of action and that address the challenge of… CONTINUE READING
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