Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease.

Abstract

The secreted Frizzled-related proteins (SFRPs) are a family of soluble proteins that are structurally related to Frizzled (Fz) proteins, the serpentine receptors that mediate the extensively used cell-cell communication pathway involving Wnt signalling. Because of their homology with the Wnt-binding domain on the Fz receptors, SFRPs were immediately… (More)
DOI: 10.1242/jcs.026096

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@article{Bovolenta2008BeyondWI, title={Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease.}, author={Paola Bovolenta and Pilar Esteve and Jos{\'e} Mar{\'i}a Ruiz and Elsa Cisneros and Javier L{\'o}pez-R{\'i}os}, journal={Journal of cell science}, year={2008}, volume={121 Pt 6}, pages={737-46} }