Beyond Missing Heritability: Prediction of Complex Traits

  title={Beyond Missing Heritability: Prediction of Complex Traits},
  author={Robert Makowsky and Nicholas M. Pajewski and Yann C. Klimentidis and Ana Iris Fr{\'i}as V{\'a}zquez and Christine W. Duarte and David B. Allison and Gustavo de Los Campos},
  booktitle={PLoS genetics},
Despite rapid advances in genomic technology, our ability to account for phenotypic variation using genetic information remains limited for many traits. This has unfortunately resulted in limited application of genetic data towards preventive and personalized medicine, one of the primary impetuses of genome-wide association studies. Recently, a large proportion of the "missing heritability" for human height was statistically explained by modeling thousands of single nucleotide polymorphisms… CONTINUE READING
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