Beyond Epithelial to Mesenchymal Transition: A Novel Role for the Transcription Factor Snail in Inflammation and Wound Healing

@article{Hotz2009BeyondET,
  title={Beyond Epithelial to Mesenchymal Transition: A Novel Role for the Transcription Factor Snail in Inflammation and Wound Healing},
  author={B. Kaser Hotz and Alexander Visekruna and H. -J. Buhr and Hubert Georg Hotz},
  journal={Journal of Gastrointestinal Surgery},
  year={2009},
  volume={14},
  pages={388-397}
}
Snail, a transcription factor linked to epithelial to mesenchymal transition (EMT) during embryonic development and tumor progression, is associated with migration of cells. During inflammation and tissue injury, cell movement is also observed to provide the first line of defense against bacteria and to promote wound healing. Therefore, we studied the function of Snail in activated macrophages in a variety of inflammatory processes. In this study, we examined the expression and localization of… CONTINUE READING

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