Beyond DNA: integrating inclusive inheritance into an extended theory of evolution

@article{Danchin2011BeyondDI,
  title={Beyond DNA: integrating inclusive inheritance into an extended theory of evolution},
  author={Etienne G. J. Danchin and Anne Charmantier and Frances A. Champagne and Alex Mesoudi and Benoit Pujol and Simon Blanchet},
  journal={Nature Reviews Genetics},
  year={2011},
  volume={12},
  pages={475-486}
}
Many biologists are calling for an 'extended evolutionary synthesis' that would 'modernize the modern synthesis' of evolution. Biological information is typically considered as being transmitted across generations by the DNA sequence alone, but accumulating evidence indicates that both genetic and non-genetic inheritance, and the interactions between them, have important effects on evolutionary outcomes. We review the evidence for such effects of epigenetic, ecological and cultural inheritance… 
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References

SHOWING 1-10 OF 216 REFERENCES
Nongenetic Inheritance and Its Evolutionary Implications
TLDR
This framework shows that, by decoupling phenotypic change from the genotype, nongenetic inheritance can circumvent the limitations of genetic inheritance and thereby influence population dynamics and alter the fitness landscape.
Inclusive heritability: combining genetic and non-genetic information to study animal behavior and culture
TLDR
This work builds on the tools of quantitative genetics and offers the concept of ‘inclusive heritability’ which identifies and unifies the various mechanisms of information transmission across generations and may advance the integration of multiple forms of inheritance into the study of evolution.
Genetic basis of fitness differences in natural populations
TLDR
An emerging understanding of the quantitative genetics of fitness variation in the wild means that the authors are poised to see a synthesis of ecological and molecular approaches in evolutionary biology.
THE EVOLUTION OF MATERNAL CHARACTERS
We develop quantitative‐genetic models for the evolution of multiple traits under maternal inheritance, in which traits are transmitted through non‐Mendelian as well as Mendelian mechanisms, and
THE LOCUS OF EVOLUTION: EVO DEVO AND THE GENETICS OF ADAPTATION
TLDR
There is no theoretical or empirical basis for the evo devo contention that adaptations involving morphology evolve by genetic mechanisms different from those involving physiology and other traits, and substantial data on the genetic basis of adaptation from both genome-wide surveys and single-locus studies are examined.
Cultural and biological evolutionary processes: gene-culture disequilibrium.
TLDR
The dynamics of the interaction between genetic and cultural transmission are studied by using a simple two-phenotype diallelic haploid genetic system and the genotype allowing the strongest transmission of the favored phenotype is successful.
INCIDENCE AND CONSEQUENCES OF INHERITED ENVIRONMENTAL EFFECTS
TLDR
From these results one can conclude that the impact of inherited environmental effects arising from these pathways is documented for a diversity of plant and animal taxa.
Inherited epigenetic variation — revisiting soft inheritance
TLDR
The line between these two components is blurred by inherited epigenetic variation, which is potentially sensitive to environmental inputs.
Epigenetics for ecologists.
TLDR
Ecologists should start using a combination of experimental approaches borrowed from ecological genetics, novel techniques to analyse and manipulate epigenetic variation, and genomic tools, to investigate the extent and structure of epigenetics variation within and among natural populations, as well as the interrelations between epigenetic variations, phenotypic variation and ecological interactions.
...
...