Bevacizumab neutralizes the protective effect of vascular endothelial growth factor on retinal ganglion cells

@inproceedings{Brar2010BevacizumabNT,
  title={Bevacizumab neutralizes the protective effect of vascular endothelial growth factor on retinal ganglion cells},
  author={Vikram S. Brar and Rajesh Kumar Sharma and Ravi K. Murthy and K. V. Chalam},
  booktitle={Molecular vision},
  year={2010}
}
PURPOSE Vascular endothelial growth factor (VEGF) is well known for its role in pathologic neovascularization, including wet age-related macular degeneration. However, a growing body of evidence indicates that VEGF is also neuroprotective of non-vascular cells in various animal models through reduction of oxidative stress. In light of the widespread use of intraocular anti-VEGF therapies for age-related macular degeneration (AMD), we evaluated the impact of anti-VEGF agents on the… CONTINUE READING
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