Between-cow variation in dermal fibroblast response to lipopolysaccharide reflected in resolution of inflammation during Escherichia coli mastitis.

@article{Kandasamy2011BetweencowVI,
  title={Between-cow variation in dermal fibroblast response to lipopolysaccharide reflected in resolution of inflammation during Escherichia coli mastitis.},
  author={Saravanakumar Kandasamy and Benjamin B. Green and Aimee L. Benjamin and David E. Kerr},
  journal={Journal of dairy science},
  year={2011},
  volume={94 12},
  pages={5963-75}
}
Effective response to mammary gland infection depends on efficient early innate immune response. The desired response would be one that is sufficient to clear the infection with a rapid return to the production of high-quality milk and limited tissue damage. In this study, 43 early lactation cows were ranked based on the ability of their fibroblasts to produce IL-8 in response to Escherichia coli lipopolysaccharide. Subsequently, the effect of a low or high response phenotype on the response to… CONTINUE READING
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