Betting odds and genetic associations.

  title={Betting odds and genetic associations.},
  author={Duncan C Thomas and David G Clayton},
  journal={Journal of the National Cancer Institute},
  volume={96 6},
“Multiple Comparisons? No Problem!” read the title of an editorial in an issue ofEpidemiologyin 1991 (1). Attitudes toward multiple comparisons have swung like a pendulum, the view quoted above representing one end of a cycle that has been reversed in recent years. Few classical risk factor epidemiology studies test more than a few hundred associations between exposures and diseases, even in an exploratory mode. In molecular epidemiology, however, the growing feasibility of testing many… CONTINUE READING