Better allele-level matching improves transplant-related mortality after double cord blood transplantation.

  title={Better allele-level matching improves transplant-related mortality after double cord blood transplantation.},
  author={Bet{\"u}l Oran and Kai Cao and Rima Saliba and K Rezvani and Marcos de Lima and Sairah Ahmed and Chitra M Hosing and Uday R Popat and Yudith Carmazzi and Partow Kebriaei and Yago L. Nieto and Gabriela Rond{\'o}n and Dana Willis and Nina Shah and Simrit Parmar and Amanda L Olson and Brandt Moore and D. W. Marin and Rohtesh S. Mehta and Marcelo An{\'i}bal Fern{\'a}ndez-Vi{\~n}a and Richard E. Champlin and Elizabeth J Shpall},
  volume={100 10},
Cord blood transplant requires less stringent human leukocyte antigen matching than unrelated donors. In 133 patients with hematologic malignancies who engrafted after double cord blood transplantation with a dominant unit, we studied the effect of high resolution testing at 4 loci (-A, -B, -C, -DRB1) for its impact on 2-year transplant-related mortality. Ten percent of the dominant cord blood units were matched at 7-8/8 alleles using HLA-A, -B, -C, and -DRB1; 25% were matched at 6/8, 40% at 5… CONTINUE READING


Publications citing this paper.
Showing 1-8 of 8 extracted citations


Publications referenced by this paper.
Showing 1-10 of 36 references

Ex Vivo Fucosylation Of Cord Blood Accelerates Neutrophil and Platelet Engraftment

  • RS Mehta, A DiStasi, BS Andersson
  • 2015

General and Virus - Specific Immune Cell Reconstitution Following Double Cord Blood Transplantation

  • D Przepiorka, D Weisdorf, P Martin
  • Biol Blood Marrow Transplant
  • 2015

The development of a myeloablative , reduced - toxicity , conditioning regimen for cord blood transplantation

  • CG Brunstein, M Eapen, KW Ahn
  • Clin Lymphoma Myeloma Leuk
  • 2014

transplantation for hematologic malignancy

  • SS Kelly, CB Sola, M deLima
  • 2014

Similar Papers

Loading similar papers…