Betaine or taurine administration prevents fibrosis and lipid peroxidation induced by rat liver by ethanol plus carbon tetrachloride intoxication

@article{Erman2004BetaineOT,
  title={Betaine or taurine administration prevents fibrosis and lipid peroxidation induced by rat liver by ethanol plus carbon tetrachloride intoxication},
  author={Frazilet Erman and Jale Balkan and Uǧur Çevikbaş and N Koçak-Toker and M. Ozan Uysal},
  journal={Amino Acids},
  year={2004},
  volume={27},
  pages={199-205}
}
The aim of this study was to investigate the effect of betaine or taurine on liver fibrogenesis and lipid peroxidation in rats. Fibrosis was induced by treatment of rats with drinking water containing 5% ethanol and CCl4 (2 × weekly, 0.2 ml/kg, i.p.) for 4 weeks. Ethanol plus CCl4 treatment caused increased lipid peroxidation and disturbed antioxidant system in the liver. Histopathological findings suggested that the development of liver fibrosis was prevented in rats treated with betaine or… CONTINUE READING