Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene.

@article{Sunden1997BetainehomocysteineME,
  title={Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene.},
  author={S L Sunden and M S Renduchintala and Eric I. Park and Steven D. Miklasz and Timothy A. Garrow},
  journal={Archives of biochemistry and biophysics},
  year={1997},
  volume={345 1},
  pages={171-4}
}
We have prepared antibodies against porcine liver betaine-homocysteine methyltransferase (BHMT; EC 2.1.1.5) and recently cloned cDNAs encoding the porcine and human liver enzymes. Porcine tissues were evaluated for BHMT expression by measuring catalytic activity and Western analysis. Liver and kidney were the only organs tested that had immunodetectable levels of BHMT, and these organs expressed high levels of enzyme activity. BHMT was expressed in the kidney cortex and not the medulla. Porcine… CONTINUE READING

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