Betaine homocysteine methyltransferase (BHMT) as a specific and sensitive blood marker for acute liver injury.


We developed a high-performance ELISA assay and measured serum BHMT levels in healthy individuals and patients with acute liver injury (ALI). The detection range of this ELISA assay was from 1.56 to 100 ng/ml. BHMT levels are significantly higher in ALI groups. In the healthy group (n = 244), the median value (interquartile range, IQR 0-56.40) was 1.83 ng… (More)
DOI: 10.3109/1354750X.2014.951880