Beta3-adrenoceptors in the cardiovascular system.

  title={Beta3-adrenoceptors in the cardiovascular system.},
  author={Catherine Gauthier and Dominique Langin and Jean-Luc Balligand},
  journal={Trends in pharmacological sciences},
  volume={21 11},
beta-Adrenoceptors of the beta1 and beta2 subtypes classically mediate the effects of catecholamines on the contractility of cardiac muscle and the relaxation of vascular smooth muscle. Since the molecular characterization of the beta3-adrenoceptor in 1989, most studies of this adrenoceptor subtype have focused on its control of lipolysis in adipose tissues. However, more recent studies have investigated the involvement of beta3-adrenoceptors in the physiological control of cardiac and vascular… CONTINUE READING


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