Beta-oxidation of 2-ethyl-5-carboxypentyl phthalate in rodent liver.

@article{Albro1987BetaoxidationO2,
  title={Beta-oxidation of 2-ethyl-5-carboxypentyl phthalate in rodent liver.},
  author={Phillip W. Albro and Jean T. Corbett and Joanna L. Schroeder and Judy K. Reddy},
  journal={Biochimica et biophysica acta},
  year={1987},
  volume={923 2},
  pages={
          196-205
        }
}
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Mono-2-ethylhexyl phthalate, a metabolite of di-(2-ethylhexyl) phthalate, causally linked to testicular atrophy in rats.

Measurement of eight urinary metabolites of di(2-ethylhexyl) phthalate as biomarkers for human exposure assessment

Differences were found between the DEHP metabolite profile between this adult population and that of six neonates exposed to high doses of DEHP through extensive medical treatment.

Effects of chronic di(2-ethylhexyl) phthalate intake on the secretion and removal rate of triglyceride-rich lipoproteins in rats.

  • N. MocchiuttiC. Bernal
  • Biology, Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1997

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Possible Mechanisms in Hepatocarcinogensis by the Peroxisome Proliferator Di(2-Ethylhexyl)Phthalate

Metabolism of di(2-ethylhexyl)phthalate.

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Comparative morphometric and biochemical data from rats treated with varying dose levels of ciprofibrate, a hypolipidemic drug, and di(2-ethylhexyl) phthalate, and the widely used plasticizers, indicate that the hepatocarcinogenic potency of these agents is correlatable with their ability to induce peroxisome proliferation,peroxisomal beta-oxidation and PPA-80.

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