Beta oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats


NEFA play a key role in the setting of insulin resistance and hyperinsulinaemia, which are both features of the prediabetic state. In addition to the direct effects on pancreas and peripheral tissues, NEFA have been reported to act via changes in autonomic nervous system activity. The present study was aimed at studying the effects of a local increase in… (More)
DOI: 10.1007/s00125-004-1569-2


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