Beta-lactam resistance in clinical isolates of Escherichia coli caused by elevated production of the ampC-mediated chromosomal beta-lactamase.

@article{Bergstrm1979BetalactamRI,
  title={Beta-lactam resistance in clinical isolates of Escherichia coli caused by elevated production of the ampC-mediated chromosomal beta-lactamase.},
  author={Sven Bergstr{\"o}m and Staffan J. Normark},
  journal={Antimicrobial agents and chemotherapy},
  year={1979},
  volume={16 4},
  pages={427-33}
}
Among cephalothin-resistant isolates from patients with urinary tract infections, six Escherichia coli strains were found to produce elevated amounts of a beta-lactamase indistinguishable from that coded by the ampC gene of E. coli K-12. The resistance levels displayed by these isolates toward a number of beta-lactams were, for five of them, considerably… CONTINUE READING